Stavudine is phosphorylated by cellular kinases to the active metabolite stavudine triphosphate 司他夫定通過(guò)細(xì)胞激酶磷酸化,形成司他夫定的三磷酸鹽而發(fā)揮抗病毒活性。
The fact that stevioside is glycosylated at position c13 could explain the absence of mutagenicity . the active metabolite of steviol responsible for its mutagenic activity is not known 甜菊糖?的c13位置被糖基化,是沒(méi)有引起突變的原因。目前,還沒(méi)有找出引發(fā)突變能力的甜菊醇活性代謝物。
An active metabolite was obtained by purification with precipitated by ethanol , sephadex g - 25 gel , deae - cellulose ion exchange resin and silica gel column chromatography 經(jīng)乙醇( 95 )沉淀、 sephadexg - 25凝膠層析、 deae -纖維素離子交換層析和硅膠層析純化,得到抑制黑曲霉生長(zhǎng)的單一組分。
The biological characterization and the absorption capacity of a myxobacterium nust03 for the heavy metal is investigated . an active metabolite is separated and purified from the fermentation by the nust03 研究鹽土粘細(xì)菌nusto3菌株的形態(tài)結(jié)構(gòu)、生理生化特性和吸附重金屬的能力并分離純化其胞外活性物質(zhì)。
The active metabolite of steviol responsible for its mutagenic activity is not known . while some data suggest that epoxidation may be involved in the metabolic activation of steviol , other data indicate that the active metabolite is not an epoxide 有些數(shù)據(jù)指出,甜菊醇在代謝活化的過(guò)程中,可能牽涉環(huán)氧化作用,但其他數(shù)據(jù)顯示,甜菊醇的活性代謝物并不是環(huán)氧化物。